Depression Health Center

People with depressive illnesses do not all experience the same symptoms. The severity, frequency, and duration of symptoms vary depending on the individual and his or her particular illness. Signs and symptoms include:

  • persistent sad, anxious, or "empty" feelings
  • feelings of hopelessness or pessimism
  • feelings of guilt, worthlessness, or helplessness
  • irritability, restlessness
  • loss of interest in activities or hobbies once pleasurable, including sex
  • fatigue and decreased energy
  • difficulty concentrating, remembering details, and making decisions
  • insomnia, early-morning wakefulness, or excessive sleeping
  • overeating, or appetite loss
  • thoughts of suicide, suicide attempts
  • aches or pains, headaches, cramps, or digestive problems that do not ease even with treatment
Review Date: 
March 13, 2012
Last Updated:
June 30, 2013