There is no sole cause of panic disorder. Panic disorder sometimes runs in families, suggesting that inheritance plays a strong role in determining who will get it. No one knows for sure why some people have it, while others don't. When chemicals in the brain are not at a certain level it can cause a person to have panic disorder. That is why medications often help with symptoms because they help the brain chemicals stay at the correct levels.
Researchers have found that several parts of the brain are involved in fear and anxiety. By learning more about fear and anxiety in the brain, scientists may be able to create better treatments. Researchers are also looking for ways in which stress and environmental factors may play a role.