Accolate (generic: zafirlukast) is a prescription medication used to prevent asthma attacks. This medication belongs to a group of drugs called leukotriene receptor antagonists. It works by blocking the actions of leukotriene, a natural substance that causes swelling and tightening of the airways.

Accolate comes in tablet form. It is usually taken twice daily on an empty stomach, 1 hour before, or 2 hours after a meal.

Common side effects include headache, nausea, and loss of appetite.