Alendronate/cholecalciferol is a prescription medication used to treat and prevent osteoporosis in men and women. It is a single tablet containing 2 medications. Alendronate belongs to a group of medications called bisphosphonates, which work by preventing bone breakdown and increasing bone density. Cholecalciferol, a form of vitamin D, is important for calcium absorption and bone health.

This medication comes in tablet form and is usually taken once a week. Always take alendronate/cholecalciferol on an empty stomach.

Common side effects include stomach pain, heartburn, and constipation.