Aplenzin (generic: bupropion) is a prescription medication used to treat depression in adults.  Aplenzin is a once-daily, long-acting version of bupropion.

Aplenzin, an antidepressant, belongs to a group of drugs called norepinephrine and dopamine reuptake inhibitors, or NDRIs. These medications are thought to improve mood by balancing certain natural chemicals in the brain.

This medication comes in tablet form and is taken once a day, with or without food.

Some of the common side effects of Aplenzin include dry mouth, nausea and trouble sleeping.  Do not take Aplenzin with alcohol. Aplenzin may cause dizziness and can impair your ability to drive.