Combivir (generic: lamivudine/zidovudine) is a prescription medication used to treat human immunodeficiency virus (HIV) infection. It is a single tablet containing 2 medications, lamivudine and zidovudine. They belong to a group of drugs called nucleoside reverse transcriptase inhibitors (NRTIs) which stop the virus from replicating.

This medication comes in tablet form and is usually taken twice daily, with or without food.

Common side effects of Combivir include nausea, vomiting, headaches, and tiredness.