Complera (generic: emtricitabine/rilpivirine/tenofovir) is a prescription medication used to treat HIV (Human Immunodeficiency Virus) which causes acquired immunodeficiency syndrome (AIDs) in adults. It is a single tablet that contains three prescription medicines, emtricitabine, rilpivirine, and tenofovirIn. For HIV to reproduce, it must convert its genetic material from RNA to DNA. These three antiviral medications stop the DNA from being made.

This medication comes in tablet form and is taken once a day, with food.

Common side effects of Complera include trouble sleeping (insomnia), abnormal dreams, and headache.