Enbrel is a medicine used alone or with other medications to relieve the symptoms of certain autoimmune disorders including rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis and chronic plaque psoriasis.

Enbrel is in a class of medications called tumor-necrosis factor (TNF) inhibitors. It works by blocking the action of TNF, a substance in the body that causes inflammation

Enbrel comes as a solution (liquid) in a prefilled syringe and an automatic injection device, and as a powder to be mixed with a provided liquid. Etanercept is injected subcutaneously (under the skin). It is usually injected once a week.

Some common side effects of Enbrel include seizures, bruising, bleeding, pale skin, rash, hives, itching, and difficulty breathing or swallowing.