Evamist (generic: estradiol) is a prescription medication used after menopause to reduce hot flashes. This medication belongs to a group of drugs called estrogen hormones. It works to relieve menopausal symptoms by replacing estrogen normally produced by the ovaries.

Evamist comes as a spray to apply to the skin on the inside of the forearm between the elbow and the wrist. It is applied once daily in the morning. Do not rub Evamist into the skin. Evamist spray should dry on your skin for at least 2 minutes before you get dressed, and at least one hour before you wash your skin.

Common side effects include headache, breast pain, and irregular vaginal bleeding or spotting.