Serious and life-threatening side effects can occur while taking Evista. These include blood clots and dying from stroke:

• Increased risk of blood clots in the legs (deep vein thrombosis) and lungs (pulmonary embolism) have been reported with Evista. Women who have or have had blood clots in the legs, lungs, or eyes should not take Evista.
• Women who have had a heart attack or are at risk for a heart attack may have an increased risk of dying from stroke when taking Evista.

The most common side effects of Evista are:

• hot flashes
• leg cramps
• swelling of the feet, ankles, and legs
• flu-like syndrome
• joint pain
• sweating (hot flashes are common during the first 6 months after starting treatment)

These are not all the possible side effects of Evista. Tell your doctor about any side effect that is bothersome or that does not go away.