Janumet XR (generic: sitagliptin/metformin) is a prescription medication used to treat type 2 diabetes in adults.  Janumet XR is an extended-release tablet containing two prescription drugs. Sitagliptin belongs to a group of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, which help lower blood sugar levels.  Metformin belongs to a group of drugs called biguanides, which decrease the amount of sugar made by the liver and help cells to respond to insulin.

This medication comes in tablet form and is taken once a day, with meals. Swallow Janumet XR tablets whole.

Common side effects of Janumet XR include stuffy nose, sore throat, nausea, and diarrhea.