Juxtapid (generic: lomitapide) is a prescription medication used to treat high cholesterol in adults with homozygous familial hypercholesterolemia (HoFA), a rare inherited disorder in which the body is unable to remove low-density lipoprotein (LDL) "bad" cholesterol from the blood.

Juxtapid belongs to a group of drugs called microsomal triglyceride transfer protein (MTP) inhibitors, which help lower cholesterol levels.

This medication comes in capsule form and is taken once a day, at least 2 hours after an evening meal, with water.

Common side effects of Juxtapid include diarrhea, nausea, and vomiting.  Do not drink grapefruit juice or more than one alcoholic beverage a day while taking Juxtapid.