Lamictal Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Lamictal and other medicines may affect each other. Always check with your doctor before starting or stopping any medicines. Especially tell your doctor if you take:

  • valproic acid (Depakene);
  • divalproex (Depakote);
  • methotrexate (Rheumatrex, Trexall); other medications for seizures such as carbamazepine (Tegretol), oxcarbazepine (Trileptal), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), and primidone (Mysoline);
  • pyrimethamine (Daraprim);
  • rifampin (Rifadin, Rimactane);
  • trimethoprim (Proloprim);
  • hormonal contraceptives (birth control pills, patches, rings, injections, implants, or intrauterine devices)
  • hormone replacement therapy medicines (estrogens, progestins and combination medicines)