Myorisan (generic: isotretinoin) is a prescription medication used to treat the most severe form of acne called nodular acne. Myorisan belongs to a group of drugs called retinoids. It is thought that retinoids work by preventing oil production in sebaceous glands.

This medication comes in capsule form and is taken twice daily, with food. Myorisan is usually taken for four or five months.

Common side effects of Myorisan include dry skin, chapped lips, dry eyes, or dry nose causing nosebleeds. Myorisan can also cause birth defects, miscarriages, or premature births.

Because Myorisan can cause birth defects, patients, doctors, and pharmacies must be registered with a special distribution program called the iPLEDGE program.