Nexavar may cause serious side effects, including:

• decreased blood flow to the heart and heart attack. Get emergency help right away and call your doctor if you get symptoms such as chest pain, shortness of breath, feel lightheaded or faint, nausea, vomiting, sweating a lot. 
• bleeding problems. Nexavar may increase your chance of bleeding. Tell your doctor if you have any bleeding while taking Nexavar. 
• high blood pressure. Your blood pressure should be checked every week during the first 6 weeks of starting Nexavar. Your blood pressure should be checked regularly and any high blood pressure should be treated while you are receiving Nexavar. 
• a skin problem called hand-foot skin reaction. This causes redness, pain, swelling, or blisters on the palms of your hands or soles of your feet. If you get this side effect, your doctor may change your dose or stop treatment for some time. 
• perforation of the bowel. Tell your doctor right away if you get high fever, nausea, vomiting, severe abdominal pain. 
• possible wound healing problems. If you need to have a surgical or dental procedure, tell your doctor that you are taking Nexavar. Nexavar may need to be stopped until your wound heals after some types of surgery. 
• birth defects or death of an unborn baby. 


Other side effects with Nexavar may include:

• rash, redness, itching or peeling of your skin 
• hair thinning or patchy hair loss 
• diarrhea (frequent or loose bowel movements) 
• nausea or vomiting 
• mouth sores 
• weakness 
• loss of appetite 
• numbness, tingling or pain in your hands and feet 
• abdominal pain 
• tiredness 
• weight loss


Tell your doctor if you have any side effects that bother you or that do not go away. These are not all the side effects with Nexavar. Ask your doctor or pharmacist for more information.