Side Effects of Orencia

Orencia can cause serious side effects including:

  • infections. Orencia can make you more likely to get infections or make the infection that you have get worse. Some patients have died from these infections. Call your healthcare provider right away if you have any symptoms of an infection. Symptoms of an infection may include:
    • fever
    • feel very tired
    • have a cough
    • have flu-like symptoms
    • warm, red, or painful skin
  • allergic reactions. Allergic reactions can happen to people who use Orencia. Call your healthcare provider or go to the emergency room right away if you have any symptoms of an allergic reaction. Symptoms of an allergic reaction may include:
    • hives
    • swollen face, eyelids, lips, or tongue
    • trouble breathing
  • hepatitis B infection in people who carry the virus in their blood. If you are a carrier of the hepatitis B virus (a virus that affects the liver), the virus can become active while you use Orencia. Your healthcare provider may do a blood test before you start treatment with Orencia while you use Orencia.
  • vaccinations. You should not receive Orencia with certain types of vaccines (live vaccines). Orencia may also cause some vaccinations to be less effective. Talk with your healthcare provider about your vaccination plans.
  • breathing problems in patients with Chronic Obstructive Pulmonary Disease (COPD). Some people may get certain respiratory problems more often if you receive Orencia and have COPD. Symptoms of respiratory problems include:
    • COPD that becomes worse
    • cough
    • trouble breathing
  • cancer (malignancies). Certain kinds of cancer have been reported in people using Orencia. It is not known if Orencia increases your chance of getting certain kinds of cancer.

Common side effects of Orencia include:

  • headache
  • upper respiratory tract infection
  • sore throat
  • nausea

In children and adolescents, other side effects may include:

  • diarrhea
  • cough
  • fever
  • abdominal pain

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Orencia. For more information, ask your healthcare provider or pharmacist.