Pomalyst (generic: pomalidomide) is a prescription medication used to treat people with multiple myeloma, a form of blood cancer that arises from cells of the bone marrow, whose cancer has progressed after being treated with other medicines. Pomalyst belongs to a group of drugs called immunomodulators that affect the immune system causing it to destroy cancer cells and inhibit their growth.

This medication comes in capsule form and is taken once daily on an empty stomach. Swallow Pomalyst capsules whole with water.

Common side effects of Pomalyst include a decrease in infection-fighting white blood cells, tiredness, weakness, and constipation.

Because Pomalyst can cause birth defects, Pomalyst is only available through a restricted distribution program called Pomalyst REMS.