Reclast (generic: zoledronic acid) is a prescription medication used to treat and prevent osteoporosis (thinning and weakening of bones) and Paget's disease in adults.  Reclast belongs to a group of drugs called biphosphonates, which slow the breakdown of bones.

This medication comes in an injectable form to be given directly into the vein (IV) by a healthcare provider. It is given once yearly or once every 2 years (for treatment or prevention of osteoporosis) or as a single dose for the treatment of Paget's disease.

Common side effects of Reclast include fever, pain, and headache.