Rilutek (generic: riluzole) is a prescription medication used to slow the progress of Lou Gehrig's disease, known medically as amyotrophic lateral sclerosis (ALS). It is a disease of the central nervous system that affects the ability of a person to move certain muscles. Rilutek is not a cure, but may delay the need for a breathing tube (tracheostomy).

Rilutek belongs to a group of drugs called NMDA receptor antagonists. It works by decreasing glutamate, a natural substance in the body that can damage nerve cells. 

This medication comes in tablet form. It is usually taken twice a day, every 12 hours, on an empty stomach.

Common side effects of Rilutek are weakness, nausea, and headache.