Samsca (generic: tolvaptan) is a prescription medication used in adults to help increase low sodium levels in the blood.

Samsca belongs to a group of drugs called vasopressin receptor blockers. It works by raising salt levels in the blood by removing extra body water as urine.

This medication comes in tablet form and is taken once daily with or without food.

Common side effects of Samsca include thirst, dry mouth and constipation.