Sinemet (generic: carbidopa/levodopa) is a prescription medication used to treat Parkinson's disease. Symptoms of Parkinson's disease are related to low levels of dopamine in a certain part of the brain. Sinemet is a single tablet containing two drugs, levodopa and carbidopa. Levodopa works, after it is converted to dopamine, by restoring dopamine levels in the brain. Carbidopa delays the conversion of levodopa into dopamine until it reaches the brain, and reduces the amount of levodopa needed.

Sinemet comes in as a regular tablet and an extended-release tablet (Sinemet CR). The regular tablet is usually taken 3 or 4 times daily. The extended-release tablet is usually taken 2 or 3 times daily, swallowed whole.

Common side effects include nausea, vomiting, weakness, and drowsiness. Do not drive or operate machinery until you know how it affects you.