Taclonex (generic: calcipotriene/betamethasone) is a prescription medication used to treat plaque psoriasis, a skin condition in which scaly, red, thickened patches form when the immune system becomes overactive.

Taclonex contains two active ingredients, calcipotriene and betamethasone. Calcipotriene belongs to a group of drugs called synthetic vitamin D3 derivatives, which slow the production of skin cells. Betamethasone is a corticosteroid which suppresses the immune system.

This medication comes in an ointment form and a liquid form. The liquid form is often applied to the scalp, but may be used on the body as well. Both forms are usually used once daily.

Some of the common side effects of Taclonex include itching, rash, and redness.