Triamterene/HCTZ is a prescription medication used to treat high blood pressure and edema (swelling). It is a single medication containing two drugs, triamterene and hydrochlorothiazide (HCTZ). Triamterene and hydrochlorothiazide belong to a group of drugs called diuretics, which causes the kidneys to get rid of sodium and water while holding on to potassium.

This medication comes in tablet and capsule forms and is taken once daily, with or without food.

Common side effects of triamterene/hydrochlorothiazide include frequent urination, weakness, fatigue, and headache.

Triamterene/hydrochlorothiazide can cause dizziness. Do not drive or operate heavy machinery until you know how this medication affects you.