Velcade (generic: bortezomib) is a prescription medication used to treat multiple myeloma (a cancer of the bone marrow) and mantle cell lymphoma (a cancer of the immune system). Velcade is in a class of medicines called proteasome inhibitors. These medications work by inhibiting the function of proteasomes, cellular complexes required to break down damaged or unneeded proteins inside cells, including cancer cells. The buildup of proteins causes cells to die, potentially slowing the progression of cancer.

This medication comes in an injectable form to be given directly into a vein (IV) or just under the skin by a healthcare provider. It may be given once or twice a week.

Common side effects of Velcade include weakness, upset stomach, vomiting, and diarrhea.