Vinblastine injection should be administered by individuals experienced in the administration of Vinblastine sulfate.

Caution – It is extremely important that the intravenous needle of catheter be properly positioned before any Vinblastine is injected. Leakeage into surrounding tissue during intravenous administration of Vinblastine may cause considerable irritation. If extravasation occurs, the injection should be discontinued immediately, and any remaining portion of the dose should then be introduced into another vein. Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulites.

FATAL IF GIVEN INTRATHECALLY. FOR INTRAVENOUS USE ONLY.