Vinblastine has been used in the palliative treatment of the following:

Frequently Responsive Malignancies

• Generalized Hodgkin’s disease (Stages III and IV, Ann Arbor modification of Rye staging system)
• Lymphocytic lymphoma (nodular and diffuse, poorly and well differentiated)
• Histiocytic lymphoma
• Mycosis fungoides (advanced stages)
• Advanced carcinoma of the testis
• Kaposi’s sarcoma
• Letterer-Siwe disease (histiocytosis X)

II. Less Frequently Responsive Malignancies

• Choriocarcinoma resistant to other chemotherapeutic agents
• Carcinoma of the breast, unresponsive to appropriate endocrine surgery and hormonal therapy