Xarelto is a prescription medicine used to prevent deep vein thrombosis (DVT; a blood clot, usually in the leg), which can lead to pulmonary embolism (PE; a blood clot in the lung), in people who are having hip replacement or knee replacement surgery.

Xarelto is in a class of medications called factor Xa inhibitors. It works by decreasing the clotting ability of the blood.

Xarelto comes as a tablet to take by mouth. It is usually taken once a day. The first dose should be taken at least 6 to 10 hours after surgery. Xarelto can be taken with or without food, unless you are told specifically to take it with food by your doctor or pharmacist. 

Some common side effects of Xarelto include itching and muscle spasms. Tell your doctor if any of these symptoms are severe or do not go away.