Zyban (generic: bupropion) is a prescription medication used to help people quit smoking. Zyban is an antidepressant that has also been found to be effective in helping people quit smoking when combined with smoking cessation counseling. The exact way it works is unknown, but it is believed to work by increasing certain brain chemicals.

This medication comes in tablet form and is taken twice daily.

Common side effects of Zyban include dry mouth and trouble sleeping.