stress relief

Best Stress Relief Supplements

Stress is an inescapable aspect of modern life. According to the American Psychological Association, around 75% of adults in the United States reported experiencing moderate to high levels of stress. When not managed effectively, stress can lead to significant health issues such as heart disease, high blood pressure, diabetes, and other serious conditions.

In our ever-changing world, the triggers for stress are diverse and often unavoidable. It could be work-related pressure, personal life disruptions, financial difficulties, or even just the sheer volume of information we are exposed to daily. Yet, in the realm of this fast-paced reality, we are not left without tools for managing stress. 

One increasingly sought-after approach is through natural herbs for anxiety and stress [1]. Let’s discover the best supplements for stress and anxiety, and how they work at a biological level. Understanding the nuances of these stress relief supplements can empower you to make informed decisions and potentially find an effective ally in your quest for stress relief and improved mental health. 

Ease Your Mind: A Comprehensive Guide to Best Stress-Reducing Supplements


Magnesium, a crucial mineral required by the body for hundreds of biochemical reactions, plays an important role in combating stress and anxiety. When we experience stress or anxiety, our bodies enter a state of high alert, known as the “fight or flight” response. 

One of the stress hormones, cortisol, tends to increase under such stress. This is where magnesium comes in: it can help regulate the body’s stress-response system by reducing the release of cortisol [2]. In essence, magnesium supplement acts as a natural ‘chill pill’ by supporting functions that counteract stress responses.


When faced with a stressful situation, the brain initiates a complex cascade of biochemical and physiological processes to help cope with the stressor. Several neurotransmitters are involved in this stress response, including serotonin, dopamine and norepinephrine. 5-HTP helps increase serotonin levels, balancing other neurotransmitters in the brain. This fosters positive thinking, feeling of happiness and a well-tuned mindset.


L-tyrosine stands out as the potent ally among other supplements for stress, anxiety and depression regulation. How? The essence lies in l-tyrosine’s ability to replenish dopamine levels. Dopamine is often referred to as the “feel-good” neurotransmitter as it influences motivation, pleasure, and reward. During periods of stress, dopamine levels become depleted, contributing to a negative mood. l-tyrosine acts as a precursor for dopamine synthesis, providing the necessary building blocks for its production. By restocking dopamine, this amino acid can help restore positive thinking, increase motivation, and counteract the negative impact of stress.


One of the best supplements to reduce stress is ashwagandha. Its adaptogenic and anxiolytic properties [3] help reduce cortisol, a stress hormone released by the body in response to stress. By normalizing cortisol levels, ashwagandha can reduce the physiological and psychological symptoms associated with stress and anxiety.

Additionally, ashwagandha has been found to enhance GABA receptor activity, reducing anxiety and promoting a sense of tranquility. 

Rhodiola Rosea

Rhodiola rosea is classified as an adaptogen, a natural substance that assists the body in adapting to various stressors. Rhodiola has also been found to modulate cortisol levels, helping to bring them back into balance. By normalizing cortisol production, rhodiola can reduce stress-related symptoms and promote a sense of calm.

What’s more, this herb can improve cognitive performance, including attention and mental processing speed, while reducing the cognitive impacts of stress and enhancing overall mental well-being.

Holy Basil Leaf

Holy basil leaf helps regulate the stress response in multiple ways. But at the core of its stress-relieving properties lies its ability to regulate neurotransmitter balance. Holy basil exhibits anxiolytic properties [4], meaning it helps reduce anxiety. It achieves this through its interaction with various neurotransmitters in the brain. Holy basil has been found to influence the levels of gamma-aminobutyric acid (GABA), serotonin, and dopamine – neurotransmitters that play crucial roles in regulating mood, emotions, and anxiety. 

Lemon Balm

With its mild sedative properties, lemon balm aids in relaxation and sleep quality. Restful sleep is essential for stress management, as lack of sleep can increase susceptibility to stress and exacerbate anxiety symptoms. Furthermore, lemon balm helps increase GABA levels by inhibiting the enzyme that breaks down GABA, thereby enhancing its availability. This leads to an overall calming effect on the nervous system, reducing anxiety and promoting a sense of tranquility.


Bacopa helps regulate the stress response in multiple ways. Firstly, it has been found to modulate the HPA axis, helping to normalize cortisol levels. By reducing the excessive production of cortisol, Bacopa promotes a more balanced stress response and mitigates the negative impact of chronic stress. With these antidepressant-like effects [5], bacopa also enhances cognitive function, including memory and learning abilities and improving mental clarity and resilience.

Other natural tips to reduce stress

Helpful Stress-Management Techniques 

Get Quality Sleep: Lack of sleep can heighten stress and negatively affect your mood, energy levels, and physical health. Aim for 7 to 9 hours of sleep per night. Create a relaxing bedtime routine and keep a consistent sleep schedule.

Exercise Regularly: Regular physical activity is one of the most effective ways to manage stress. Exercise stimulates the production of endorphins, chemicals in the brain that act as natural painkillers and mood elevators.

Connect with Others: Social interaction can provide a sense of belonging and self-worth, which can help you through stressful times. Make time for connecting with friends and family, joining clubs or groups, or volunteering in your community.

Manage Your Time: Prioritizing tasks, breaking projects into smaller steps, and avoiding over-commitment can help manage your workload and reduce stress.

Take Regular Breaks and Rest from Work: Our bodies and minds need time to recover from demanding routines. It’s essential to strike a healthy work-life balance. Make sure to take short breaks during the workday to rest and rejuvenate. 

Consider Supplementation: Alongside a balanced diet, certain dietary supplements can be beneficial in managing stress and anxiety. In this article we have outlined the best anti-anxiety supplements, which can be used as part of a comprehensive approach to stress management. 

Final Thoughts

In a world where stress has become a prevalent part of our daily life, it is imperative to find resources and employ strategies to combat its pervasive impact on our well-being. Ignoring stress can potentially diminish our ability to perform daily activities and deteriorate our overall health. What supplements help with anxiety most effectively? We feature the ingredients like Magnesium, 5-HTP and L-Tyrosine, alongside herbal extracts of Ashwagandha, Rhodiola, Holy Basil Leaf, lemon Balm and Bacopa. 

Taking these supplements, while incorporating other stress-management techniques, can help you better cope with stress and improve your mental resilience. These combined practices work synergistically, providing a comprehensive approach to not just manage, but also potentially prevent high levels of stress, leading to better mental well-being and quality of life.



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