Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. While Aloxi is unlikely to interact with other medicines and no interactions have been identified, not all drug interactions are known and reported and new interactions are continually being discovered.
Aloxi is a prescription medicine used to prevent nausea and vomiting that happens with certain cancer treatments (chemotherapy) or surgery in adults.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Aloxi Capsules:
- Store Aloxi capsules at 59°F to 86°F (15°C to 30°C)
- Keep Aloxi away from light
Keep Aloxi capsules out of the reach of children.
Take Aloxi exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
Surgery
The recommended intravenous (IV) Aloxi dose to prevent nausea and vomiting related to surgery is 0.075 mg. It is given directly into a vein just before surgery.
Chemotherapy
The recommended intravenous (IV) Aloxi dose is 0.25 mg. It is given 30 minutes before starting chemotherapy.
The recommended oral Aloxi dose is 0.5 mg taken by mouth one hour before chemotherapy.
Aloxi Capsules:
- Take Aloxi exactly as prescribed by your doctor.
- Take one Aloxi Capsule by mouth about one hour before you get your anti-cancer medicine (chemotherapy).
- Aloxi can be taken with or without food.
- If you take too much Aloxi, tell your doctor right away.
Aloxi IV:
Aloxi is given in your vein by I.V. (intravenous) injection. It is only given to you by a healthcare provider in a hospital or clinic. Aloxi is usually injected into your vein about 30 minutes before you get your anti-cancer medicine (chemotherapy) or immediately before anesthesia for surgery.
Serious allergic reactions. Serious allergic reactions can happen with Aloxi. Tell your doctor if you experience redness or swelling of the skin, itching, chest discomfort or shortness of breath.
The most common side effects of Aloxi are:
- headache
- constipation
- tiredness (fatigue)
Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Aloxi. For more information, ask your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
If you take too much Aloxi, call your local Poison Control Center or seek emergency medical attention right away.
The injectable form of Aloxi is usually administered by a healthcare provider in a medical setting making it unlikely for an overdose to occur. However, if overdose is suspected, seek emergency medical attention.
Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Aloxi passes into your milk. You and your doctor should decide if you will take Aloxi or breastfeed. You should not do both.
Tell your doctor about all of your medical conditions, including if you:
- have had an allergic reaction to another medicine for nausea or vomiting, such as Kytril (granisetron), Anzemet (dolasetron), Zofran (ondansetron), or to the medicine Lotronex (alosetron).
- are pregnant or plan to become pregnant. It is not known if Aloxi may harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if Aloxi passes into your milk. You and your doctor should decide if you will take Aloxi or breastfeed. You should not do both.
Tell your doctor about all of the medicines you take including prescription and nonprescription medicines, vitamins and herbal supplements.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Aloxi may harm your unborn baby. Aloxi should not be used to treat morning sickness (nausea and vomiting that is commonly associated with pregnancy).
Aloxi Capsules:
Active ingredient: palonosetron hydrochloride
Inactive ingredients: Mono-glycerides and di-glycerides of capryl/capric acid, glycerin, polyglyceryl oleate, water, and butylated hydroxyanisole
Aloxi IV:
Active ingredient: palonosetron hydrochloride
Inactive ingredients: mannitol, disodium edetate, and citrate buffer in water
Serious allergic reactions. Serious allergic reactions can happen with Aloxi. Tell your doctor if you experience redness or swelling of the skin, itching, chest discomfort or shortness of breath.
Aloxi (generic: palonosetron) is a prescription medication used to treat nausea and vomiting caused by certain cancer treatments or surgery. Aloxi belongs to a group of drugs called 5-HT3 receptor antagonists, which block a natural substance called serotonin from causing nausea and vomiting.
This medication comes in capsule form and in an injectable form. The capsules are taken one hour before cancer treatments, with or without food. The injection is given by IV (into your vein) by a healthcare provider around 30 minutes before cancer treatments. For surgery, the IV form is given just before anesthesia is started.
Common side effects of Aloxi include headache, constipation, and tiredness.