Aubagio is a prescription medicine used to treat adults with relapsing forms of multiple sclerosis (MS). Aubagio can decrease the number of MS flare-ups (relapses). Aubagio does not cure MS, but it can help slow down the physical problems that MS causes.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
WARNING: HEPATOTOXICITY and RISK OF TERATOGENICITY
Aubagio may cause serious side effects, including:
- within 6 months before you start taking Aubagio
- 1 time a month for 6 months after you start taking Aubagio
- nausea
- vomiting
- stomach pain
- loss of appetite
- tiredness
- your skin or the whites of your eyes turn yellow
- dark urine
- If you are a female, you should have a pregnancy test before you start taking Aubagio. Use effective birth control during your treatment with Aubagio.
- After stopping Aubagio, continue using effective birth control until you have blood tests to make sure your blood levels of Aubagio are low enough. If you become pregnant while taking Aubagio or within 2 years after you stop taking it, tell your doctor right away.
- Aubagio Pregnancy Registry. If you become pregnant while taking Aubagio or during the 2 years after you stop taking Aubagio, talk to your doctor about enrolling in the Aubagio Pregnancy Registry at 1800-745-4447, option 2. The purpose of this registry is to collect information about your health and your baby’s health.
- For men taking Aubagio:
- If your female partner plans to become pregnant, you should stop taking Aubagio and ask your doctor how to quickly lower the levels of Aubagio in your blood.
- If your female partner does not plan to become pregnant, you and your female partner should use effective birth control during your treatment with Aubagio. Aubagio remains in your blood after you stop taking it, so continue using effective birth control until Aubagio blood levels have been checked and they are low enough.
- have severe liver problems
- are pregnant or are of childbearing age and not using effective birth control
- take a medicine called leflunomide
Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Aubagio passes into your breast milk. You and your doctor should decide if you will take Aubagio or breastfeed. You should not do both at the same time.
Active ingredient: teriflunomide
If you take too much Aubagio, call your doctor or local Poison Control Center or seek emergency medical attention right away.
Before you receive Aubagio, and periodically after, your doctor will order blood tests and a skin test for tuberculosis.
Your doctor will tell you exactly how you should take Aubagio. Follow the directions carefully.
Aubagio is usually taken once daily, with or without food.
Aubagio (generic: teriflunomide) is a prescription medication used to treat relapsing forms of multiple sclerosis (MS) in adults. Aubagio belongs to a class of drugs called immunomodulatory drugs. The exact way it works is unknown, but may involve a reduction in the number of certain immune cells.
Aubagio comes in tablet form and is taken once a day, with or without food.
Common side effects of Aubagio include hair thinning, diarrhea, flu, nausea, and burning or prickling feelings on the skin.
- Store Aubagio at room temperature between 68°F to 77°F (20°C to 25°C).
- Keep Aubagio and all medicines out of reach of children.
Do not take Aubagio if you are pregnant. Do not take Aubagio unless you are using effective birth control. See “Drug Precautions”.
Aubagio may cause serious side effects, including:
- See “Drug Precautions”
- decreases in your white blood cell count. Your white blood cell counts should be checked before you start taking Aubagio. When you have a low white blood cell count you:
- may have more frequent infections. You should have a skin test for TB (Tuberculosis) before you start taking Aubagio. Tell your doctor if you have any of these symptoms of an infection:
- fever
- tiredness
- body aches
- chills
- nausea
- vomiting
- should not receive certain vaccinations during your treatment with Aubagio and for 6 months after your treatment with Aubagio ends.
- may have more frequent infections. You should have a skin test for TB (Tuberculosis) before you start taking Aubagio. Tell your doctor if you have any of these symptoms of an infection:
- numbness or tingling in your hands or feet that is different from your MS symptoms. You have a greater chance of getting peripheral neuropathy if you:
- are over 60 years of age
- take certain medicines that affect your nervous system
- have diabetes
- kidney problems . Tell your doctor if you have pain in your side (flank pain).
- high potassium levels in your blood. Tell your doctor if you have nausea that does not go away or a racing heartbeat.
- serious skin problems. Tell your doctor if you have any skin problems such as redness and peeling.
- new or worsening breathing problems. Tell your doctor if you have shortness of breath or coughing with or without fever.
- high blood pressure. Your doctor should check your blood pressure before you start taking Aubagio and while you are taking Aubagio.
- increases in the results of blood tests to check your liver
- hair thinning or loss (alopecia)
- diarrhea
- flu
- nausea
- burning or prickling feeling in your skin (paraesthesia)
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
The recommended dose of Aubagio is 7 mg or 14 mg taken by mouth once daily.
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Aubagio there are no specific foods that you must exclude from your diet when receiving Aubagio.
Before you take Aubagio, tell your doctor if you:
- have liver or kidney problems
- have a fever or infection, or you are unable to fight infections
- have numbness or tingling in your hands or feet that is different from your MS symptoms
- have diabetes
- have had serious skin problems when taking other medicines
- have breathing problems
- have high blood pressure
- are breastfeeding or plan to breastfeed. It is not known if Aubagio passes into your breast milk. You and your doctor should decide if you will take Aubagio or breastfeed. You should not do both at the same time.