If you take too much Axiron, call your local Poison Control Center or seek emergency medical attention right away.
Do not use Axiron if you are pregnant. It may harm your unborn baby.
Axiron (generic: testosterone) is a prescription medicine used to treat adult males with low testosterone. Axiron is in a class of medicines called endogenous androgens. It works by absorbing through the skin and delivering normal levels of testosterone.
See also “Drug Precautions”.
Axiron can cause serious side effects including:
- If you already have enlargement of your prostate gland your signs and symptoms can get worse while using Axiron. This can include:
- increased urination at night
- trouble starting your urine stream
- having to pass urine many times during the day
- having an urge that you have to go to the bathroom right away
- having a urine accident
- being unable to pass urine or weak urine flow
- Possible increased risk of prostate cancer. Your healthcare provider should check you for prostate cancer or any other prostate problems before you start and while you use Axiron.
- In large doses Axiron may lower your sperm count.
- Swelling of your ankles, feet, or body.
- Enlarged or painful breasts.
- Problems breathing while you sleep (sleep apnea).
- Blood clots in the legs. This can include pain, swelling or redness of your legs.
Call your healthcare provider right away if you have any of the serious side effects listed above.
The most common side effects of Axiron include:
- skin redness or irritation where Axiron is applied
- increased red blood cell count
- headache
- diarrhea
- vomiting
- increase in blood level of Prostate Specific Antigen (a test used to screen for prostate cancer)
Other side effects include more erections than are normal for you or erections that last a long time.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Axiron. For more information, ask your healthcare provider or pharmacist.
Store Axiron at 15°C to 30°C (59°F to 86°F).
When it is time to throw away the bottle, safely throw away all parts of the Axiron dispenser including bottle applicator cup and cap. Be careful to prevent accidental exposure of children or pets.
Keep Axiron away from fire.
Active ingredient: testosterone
Inactive ingredients: ethanol, isopropyl alcohol, octisalate, and povidone.
- It is important that you apply Axiron exactly as your healthcare provider tells you to.
- Your healthcare provider will tell you how much Axiron to apply and when to apply it.
- Your healthcare provider may change your Axiron dose. Do not change your Axiron dose without talking to your healthcare provider.
- Axiron is to be applied to the armpits only. Do not apply Axiron to any other parts of your body such as your stomach area (abdomen), penis, scrotum, shoulders or upper arms.
- Do not apply Axiron with your fingers or hands.
- Apply Axiron at about the same time each morning. Axiron should be applied after showering or bathing.
- Avoid swimming or bathing for at least 2 hours after you apply Axiron.
- You can use an antiperspirant or deodorant before applying Axiron. If you use antiperspirant or deodorant, then it should be applied at least 2 minutes before you apply Axiron.
- Axiron is flammable until dry. Let Axiron dry before smoking or going near an open flame.
- Avoid splashing in the eyes. In case of contact with eyes, flush thoroughly with water. If irritation persists, seek medical advice.
Axiron can transfer from your body to others. This can happen if other people come into contact with the area where the Axiron was applied.
Signs of puberty that are not expected (for example, pubic hair) have happened in young children who were accidentally exposed to testosterone through skin to skin contact with men using topical testosterone products like Axiron.
- Women and children should avoid contact with the unwashed or unclothed area where Axiron has been applied. If a woman or child makes contact with the application area, the contact area on the woman or child should be washed well with soap and water right away.
- To lower the risk of transfer of Axiron from your body to others, you should follow these important instructions:
- Apply Axiron only to your armpits.
- Wash your hands right away with soap and water after applying Axiron.
- After the solution has dried, cover the application area with clothing. Keep the area covered until you have washed the application area well or have showered.
- If you expect another person to have direct skin-to-skin contact with your armpits, first wash the application area well with soap and water.
Stop using Axiron and call your healthcare provider right away if you see any signs and symptoms in a child or a woman that may have occurred through accidental exposure to Axiron:
Signs and symptoms in children may include:
- enlarged penis or clitoris
- early development of pubic hair
- increased erections or sex drive
- aggressive behavior
Signs and symptoms in women may include:
- changes in body hair
- a large increase in acne
Do not use Axiron if you:
- have breast cancer
- have or might have prostate cancer
- are pregnant or may become pregnant or are breast-feeding. Axiron may harm your unborn or breast-feeding baby.
Women who are pregnant or who may become pregnant should avoid contact with the area of skin where Axiron has been applied.
Talk to your healthcare provider before taking this medicine if you have any of the above conditions.
Axiron is a prescription medicine that contains testosterone. It is used to treat adult males who have low, or no testosterone.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Do not use Axiron if you are breastfeeding. It may harm your nursing baby.
WARNING: SECONDARY EXPOSURE TO TESTOSTERONE
- Virilization has been reported in children who were secondarily exposed to topical testosterone products.
- Children should avoid contact with unwashed or unclothed application sites in men using AXIRON.
- Healthcare providers should advise patients to strictly adhere to recommended instructions for use.
Before you use Axiron, tell your healthcare provider if you:
- have breast cancer
- have or might have prostate cancer
- have urinary problems due to an enlarged prostate
- have heart problems
- have kidney or liver problems
- have problems breathing while you sleep (sleep apnea)
- have any other medical conditions
Tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Using Axiron with other medicines can affect each other.
Especially tell your healthcare provider if you take:
- insulin
- medicines that decrease blood clotting
- corticosteroids
Know the medicines you take. Ask your healthcare provider or pharmacist for a list of all of your medicines if you are not sure. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.