Diclegis may cause serious side effects, including drowsiness.
- Do not drive, operate heavy machinery, or other activities that need your full attention unless your healthcare provider says that you may do so.
- Do not drink alcohol, or take other central nervous system depressants such as cough and cold medicines, certain pain medicines, and medicines that help you sleep while you take Diclegis. Severe drowsiness can happen or become worse causing falls or accidents.
Diclegis is a prescription medicine used to treat nausea and vomiting of pregnancy in women who have not improved with change in diet or other non-medicine treatment.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Active ingredient: doxylamine succinate (an antihistamine) and pyridoxine hydrochloride (vitamin B6).
If you take too much Diclegis (overdose), you may have the following symptoms:
- restlessness
- dry mouth
- the pupils of your eyes become larger (dilated)
- sleepiness
- dizziness
- confusion
- fast heart rate
- seizures
- muscle pain or weakness
- sudden and severe kidney problems
If you have these symptoms and they are severe, they may lead to death. Stop taking Diclegis, call your healthcare provider or go to the nearest hospital emergency room right away. For more information about overdose treatment, call your local Poison Control Center.
Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Diclegis can pass into your breast milk and may harm your baby. You should not breastfeed while using Diclegis.
Diclegis (generic: doxylamine/pyridoxine) is a prescription medication used to treat nausea and vomiting of pregnancy, also known as “morning sickness”. Diclegis is a single tablet containing 2 medications, doxylamine, an antihistamine that works by blocking the effects of histamine, and pyridoxine, also known as vitamin B6.
This medication comes in an extended-release tablet to be taken whole, on an empty stomach. The recommended starting dose is two tablets taken at bedtime. If necessary, the dose can be increased to a maximum recommended dose of four tablets daily (one in the morning, one mid-afternoon and two at bedtime).
The most common side effect is drowsiness. Do not drive or operate heavy machinery until you know how Diclegis affects you.
Do not take Diclegis if you:
- are allergic to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any of the ingredients in Diclegis.
- take monoamine oxidase inhibitors (MAOIs) (Marplan, Nardil, Emsam, Eldepryl, Zelapar, Parnate)
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Diclegis there are no specific foods that you must exclude from your diet when receiving Diclegis.
- Store Diclegis between 68°F to 77°F (20°C to 25°C).
- Keep Diclegis tablets dry, in a tightly closed container, and out of the light.
- Safely throw away medicine that is out of date or no longer needed.
Before taking Diclegis, tell your healthcare provider about all of your medical conditions, including if you are breastfeeding or plan to breastfeed.
- Talk to your healthcare provider about how much Diclegis to take and when to take it.
- Take Diclegis everyday as prescribed by your healthcare provider. Do not stop taking Diclegis without talking to your healthcare provider first.
- See the following schedule for the usual way you should start taking Diclegis:
- Day 1- Take 2 tablets, by mouth at bedtime.
- Day 2- Take 2 tablets at bedtime. If your nausea and vomiting is better or controlled on Day 2, continue to take 2 tablets every night at bedtime. This will be your usual dose unless your healthcare provider tells you otherwise.
- Day 3- If you still had nausea and vomiting on Day 2, take 3 tablets on Day 3 (1 tablet in the morning and 2 tablets at bedtime).
- Day 4- If your nausea and vomiting was better or controlled on Day 3, continue to take 3 tablets each day (1 tablet in the morning and 2 tablets at bedtime). If you still had nausea and vomiting on Day 3, start taking 4 tablets each day (1 tablet in the morning, 1 tablet in the afternoon, and 2 tablets at bedtime).
- Do not take more than 4 tablets (1 in the morning, 1 in the mid-afternoon, and 2 at bedtime) in 1 day.
- Take Diclegis on an empty stomach with a glass of water.
- Take Diclegis tablets whole. Do not crush, chew, or break Diclegis tablets before swallowing. If you cannot swallow Diclegis tablets whole, tell your healthcare provider.
Tell your doctor about the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- monoamine oxidase inhibitors (MAOIs) (Marplan, Nardil, Emsam, Eldepryl, Zelapar, Parnate)
This is not a complete list of Diclegis drug interactions. Ask your doctor or pharmacist for more information.
The recommended starting dose is two tablets taken at bedtime. If necessary, the dose can be increased to a maximum recommended dose of four tablets daily (one in the morning, one mid-afternoon and two at bedtime).