Ilaris is usually administered by a healthcare provider in a medical setting making it unlikely for an overdose to occur. However, if overdose is suspected, seek emergency medical attention.
Ilaris can cause serious side effects including:
- serious infections. Symptoms of an infection may include:
- a fever lasting longer than 3 days
- a cough that does not go away
- redness in one part of your body
- warm feeling or swelling of your skin
- decrease your body’s ability to fight infections (immunosuppression)
Other serious side effects may occur while you are taking and after you finish taking Ilaris including allergic reactions.
Symptoms of an allergic reaction may include:
- rash (hives)
- swollen face
- problems breathing or swallowing
Call your healthcare provider right away or get emergency medical help if you have any of the signs of an infection or allergic reaction.
Do not take Ilaris if you are allergic to canakinumab or any of the ingredients in Ilaris.
Dosage for the treatment of CAPS
The recommended dose of Ilaris for the treatment of cryopyrin-associated periodic syndromes (CAPS) in people who weigh more than 40 kg (88 pounds) is 150 mg every eight weeks.
Active ingredients: canakinumab
Inactive ingredients: sucrose, L-histidine, L-histidine HCl monohydrate, polysorbate 80, preservative-free Sterile Water for Injection.
Ilaris (generic: canakinumab) is a prescription medication used to treat rare genetic autoinflammatory diseases known as Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells Syndrome (MWS). Ilaris is also approved to treat active systemic juvenile idiopathic arthritis (JIA) in patients aged 2 years and older.
Ilaris belongs to a group of drugs called interleukin-1beta blockers, which block a protein responsible for inflammation.
This medication comes in an injectable form to be injected just under the skin by your doctor or healthcare provider every 8 weeks.
Common side effects of Ilaris include cold symptoms, diarrhea, runny nose, and headache.
Tell your healthcare provider if you are pregnant or planning to become pregnant. It is not known if Ilaris will harm your unborn baby. Tell your healthcare provider right away if you become pregnant while taking Ilaris.
Before you take Ilaris, tell your healthcare provider if you:
- think you have an infection
- are being treated for an infection
- have signs of an infection, such as fever, cough, or flu-like symptoms
- have a history of infections that keep coming back
- have or have had HIV, Hepatitis B, or Hepatitis C
- have an immune system problem. People with these conditions have a higher chance for infections.
- have tuberculosis (TB), or if you have been in close contact with someone who has or has had tuberculosis
- are scheduled to receive any immunizations (vaccines). You should not get �?live vaccines’ if you take Ilaris.
- are pregnant or planning to become pregnant. It is not known if Ilaris will harm your unborn baby. Tell your healthcare provider right away if you become pregnant while taking Ilaris.
- are breastfeeding or planning to breastfeed. It is not known if Ilaris passes into your breast milk. You and your healthcare provider should decide if you will take Ilaris or breastfeed. You should not do both.
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements.
Tell your healthcare provider if you are breastfeeding or planning to breastfeed. It is not known if Ilaris passes into your breast milk. You and your healthcare provider should decide if you will take Ilaris or breastfeed. You should not do both.
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Especially tell your healthcare provider if you take:
- Medicines that affect your immune system
- IL-1 blocking agents such as Kineret (anakinra), Arcalyst (rilonacept)
- Tumor Necrosis Factor (TNF) inhibitors such as Enbrel (etanercept)
- Humira (adalimumab), or Remicade (infliximab)
- Medicines that can affect enzyme metabolism. Ask your healthcare provider if you are not sure.
Ask your healthcare provider or pharmacist for a list of these medicines, if you are not sure.
Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.
- Ilaris comes in the form of an injection to be given just under the skin (subcutaneously).
- Ilaris is usually given by a healthcare provider once every 8 weeks.
- Do not receive Ilaris if you have an infection.
Ilaris is a prescription medicine injected just below the skin (subcutaneous) used in adults and children 4 years and older to treat auto-inflammatory diseases known as Cryopyrin-Associated Periodic Syndromes (CAPS), including:
- Familial Cold Autoinflammatory Syndrome (FCAS)
- Muckle-Wells Syndrome (MWS)
Ilaris is also approved to treat active systemic juvenile idiopathic arthritis (JIA) in patients aged 2 years and older (approval granted May 10, 2013).
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Ilaris can cause serious side effects. See “Drug Precautions” section.
The most common side effects include:
- cold symptoms
- diarrhea
- flu (influenza)
- runny nose
- nausea
- headache
- injection site reaction (such as redness, swelling, warmth, itching)
- feeling like you are spinning (vertigo)
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Ilaris. For more information, ask your healthcare provider or pharmacist.
Call your doctor for medical advice about side effects.
You may report side effects to FDA at 1-800-FDA-1088.